What medications interact with grapefruit seed extract?

Drugs interacting with grapefruit and inducing serious clinical consequences (confirmed or very probable) include: immunosuppressants, some statins, benzodiazepines, most calcium channel blockers, indinavir and carbamazepine. There are large inter-individual differences in enzyme efficiency.

Who should not take grapefruit seed extract?

Grapefruit seed extract concentrated liquid and capsules should not be taken by children except under a doctor's supervision. Adults can mix 10 drops of the liquid concentrate into a glass of water or juice (5 oz. or more) and drink, 1-3 times daily, with or without meals.

Is grapefruit extract safe with medication?

Medications for high blood pressure (Calcium channel blockers) interacts with GRAPEFRUIT. Grapefruit juice might increase how much medication for high blood pressure the body absorbs. Drinking grapefruit juice while taking some medications for high blood pressure might cause your blood pressure to go too low.

Can grapefruit seed extract be harmful?

GSE is generally considered safe with few side effects. Dosages of around 300–800 mg per day for 8–16 weeks have been found to be safe and well tolerated in humans ( 4 ). Those who are pregnant or breastfeeding should avoid it, as there is insufficient data on its effects in these populations.

Does grapefruit seed extract interfere with statins?

Grapefruit contains a chemical that can interfere with your body's ability to break down or metabolize certain statin medications. When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.

Which medicines should not be taken together?

Dangerous and Deadly Drug Combinations

• Dangerous and Deadly Drug Combinations. Douglas S. …
• Drug/Drug Interactions.
• St John's Wort and Potentially Lifesaving Drugs.
• Serotonin Syndrome.
• Statins Plus CYP3A4 Inhibitors.
• Clarithromycin and Calcium-Channel Blockers.
• TMP/SMX and Antihypertensive Agents.
• Warfarin and Acetaminophen.

Does grapefruit seed extract interact with statins?

Grapefruit contains a chemical that can interfere with your body's ability to break down or metabolize certain statin medications. When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.