Does grapefruit seed extract effect medications?

Drugs interacting with grapefruit and inducing serious clinical consequences (confirmed or very probable) include: immunosuppressants, some statins, benzodiazepines, most calcium channel blockers, indinavir and carbamazepine. There are large inter-individual differences in enzyme efficiency.

Who should not take grapefruit seed extract?

Grapefruit seed extract concentrated liquid and capsules should not be taken by children except under a doctor's supervision. Adults can mix 10 drops of the liquid concentrate into a glass of water or juice (5 oz. or more) and drink, 1-3 times daily, with or without meals.

Can grape seed extract raise blood pressure?

Several clinical trials have shown that grape seed extract can reduce blood pressure, but the results are often irreproducible.

Can you take vitamin C with grapeseed extract?

What should I avoid while taking grape seed? It may not be safe to take vitamin C and grape seed together. This combination may raise your blood pressure. Avoid taking vitamin C and grape seed if you already have high blood pressure.

Does grapefruit seed extract interfere with statins?

Grapefruit contains a chemical that can interfere with your body's ability to break down or metabolize certain statin medications. When statin takers eat large amounts of grapefruit, the level of statins in their blood can increase, raising the possibility of side effects.

Can grapefruit seed extract be harmful?

GSE is generally considered safe with few side effects. Dosages of around 300–800 mg per day for 8–16 weeks have been found to be safe and well tolerated in humans ( 4 ). Those who are pregnant or breastfeeding should avoid it, as there is insufficient data on its effects in these populations.

What are the side effects of grape seed extract?

Grape seed extract is generally considered safe. Side effects may include headache, itchy scalp, dizziness, and nausea. Risks. People allergic to grapes should not use grape seed extract.